Large Melanosome Complex Is Increased in Keratinocytes of Solar Lentigo

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Treatment of solar lentigo with cryosurgery.

Sir, Melanocytes are the skin cells most vulnerable to cold; they can be destroyed by temperatures of ± 4 to ± 73C (1). Lower tissue temperatures or repeated freeze ± thaw applications lead to skin necrosis (2). Selective destruction of melanocytic lesions by skin freezing can therefore be achieved without epithelial loss or skin necrosis if certain technical requirements are taken into account...

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Comparison of efficacy of cryotherapy versus trichloroacetic acid in the treatment of solar lentigo on hands

Background and aim: Solar lentigines are common sun-induced benign melanocytic proliferations that present a significant cosmetic problem for many middle- aged and elderly patients. The purpose of this study was to assess the efficacy of cryotherapy in comparison to trichloroacetic acid (TCA) 33% on solar lentigines on the back of the hands (SLBH).Materials and Methods:...

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Efficacy and Side Effects of Trichloroacetic Acid (TCA) Versus Cryotherapy in the Treatment of Solar Lentigo

Introduction: Solar lentigo is local and benign proliferation of melanocytes which is common in old individuals and creates a major concern considering beauty. Despite several and somehow expensive treatments such as laser and cryotherapy, chemical peeling with Trichloroacetic Acid (TCA) has recently attracted attentions considering its low cost and availability. The present study was des...

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Filopodia are conduits for melanosome transfer to keratinocytes.

Melanosomes are specialized melanin-synthesizing organelles critical for photoprotection in the skin. Melanosome transfer to keratinocytes, which involves whole organelle donation to another cell, is a unique biological process and is poorly understood. Time-lapse digital movies and electron microscopy show that filopodia from melanocyte dendrites serve as conduits for melanosome transfer to ke...

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ژورنال

عنوان ژورنال: Cosmetics

سال: 2017

ISSN: 2079-9284

DOI: 10.3390/cosmetics4040049